Located at 4201 Main St. in the heart of Ion District, the Ion building is the namesake centerpiece of Houston’s innovation corridor, anchoring a district-wide vision to advance and sustain Houston’s economic resilience—and deliver a better quality of life for each other.
Ion
Houston’s HQ for Innovation.
Bringing Houston’s entrepreneurial, corporate, and academic communities into collaborative spaces and programs where ideas go to grow.
Ion Directory
Building Resources
Food & Drink
Offices
- ActivateL3
- Aikynetix – NexusL3
- Ampla – Nexus (Coming Soon)L3
- Ara PartnersL3
- Artemis Energy PartnersL5
- Athenian GroupL2
- Baker Botts – NexusL3
- BeONE Sports – NexusL3
- BigMachine AI – NexusL3
- Carbon CleanL2
- CES RenewablesL5
- ChevronL3
- CogniteL3
- Dialysafe – NexusL3
- DirectH2 – NexusL3
- EasilyBEE – NexusL3
- EleoxL5
- Energy Transition Ventures – NexusL3
- Fathom FundL2
- Feather Medical – Nexus (Coming Soon)L3
- Fitz Gate Ventures – NexusL3
- Fortamis – Nexus (Coming Soon)L3
- Goose Capital – NexusL3
- GreenflashL4
- HealthSeers – NexusL3
- HEXAspec – NexusL3
- Houston Methodist Tech HubLL
- Impact Hub HoustonLL
- Industrious – CoworkingL2/L4
- Innovation NorwayL2
- Ion + Rice Alliance TeamL1
- IronLattice – NexusL3
- Kinnections – NexusL3
- Kongsberg DigitalL5
- LabShare – NexusL3
- LiftBio Labs – Nexus (Coming Soon)L3
- LineupsL2
- LiongardL4
- Lumino Technologies, IncL2
- MicrosoftL5
- More Than Capital – NexusL3
- Netherlands Business Support Office (NBSO) TexasL2
- OpenStaxL3
- OxyL4
- Per ScholasLL
- Persona AIL1
- RedSwan CREL3
- Rice Business Executive EducationLL
- Rice NexusL3
- Rice Space Institute – NexusL3
- Rivsal – NexusL3
- SibmeL2
- Simulos – NexusL3
- Social Design Lab – NexusL3
- Taurus Vascular – NexusL3
- Tether – NexusL3
- TheOCR – Nexus (Coming Soon)L3
- Train Genomics – NexusL3
- TranswesternLL
- UBiosis Health – NexusL3
- Van Holland Group Inc.L2
- Veloci Running – NexusL3
- ViotasL2
- Woodside Energy – NexusL3
- None
About Ion
It starts at the Ion:
Where ideas go to grow.
The beautifully revived building—once home to the iconic Sears showroom, itself a modern marvel in 1939—is today a sunlit structure of steel and glass designed to bring Houston’s entrepreneurial, corporate, and academic communities into collaborative spaces and programs. A place for turning imagination and ideas into tangible realities.
From Fortune 500s seeking flexible office space to first-time startups looking for the funding to build a prototype, the Ion invites individuals and teams of all kinds to a place where they can break with convention, break into the tech scene, or simply break up their day with a coffee and easy atmosphere. Anyone is welcome at any time.
Specifications
266,000 SF
Total space (office, academic, and retail space)
86,000 SF
Coworking space
50,000 SF
Public and shared building resources
6 Levels
Including a lower level & 5 floors above ground
Forum Stairs
250-seat event space for panels, fireside chats, and more.
Ion Plaza
1/2-acre of wired outdoor space